Abstract: In the exploitation process of high gassy coal mine, in order to prevent the accumulation of gas , gas drainage is mainly used to reduce the gas concentration in goaf. However, gas extraction will increase gob air leakage and result in complex air flow in gob. So, how to handle the gob gas drainage and fire prevention relationships becomes a major problem. This paper analyzed comprehensive management of gas drainage and goaf fire extinguishing measures in 335 working face of Rujigou Coal Mine, and found the suitable treatments of fire prevention and extinguishing methods for 335 goaf in Rujigou Coal Mine.