Abstract: The float coal spontaneous combustion in Bulianta Coal Mine 22305 working face overlying coal gob area of Shendong coal company caused a large area gob fire. Based on the analysis of domestic and foreign research present situation of fire prevention, the paper determined control measures of the cooling and oxygen-consumed, and the comprehensive treatment for sealing fire area with perfusion of liquid inert gases, grouting and other measures were conducted. Eventually, fire zone index gas such as CO dropped to controllable range, and the safe working conditions was achieved.