Abstract: Due to the high concentration and overrun possibility of harmful gases(gas and CO₂) on 1101 working face of Fujiaao coal mine with spontaneous combustion coal seam,which combined with the harmful gas will be prone to coal spontaneous combustion,even explosion,fire prevention and extinguishing technology,based on pressure ventilation and grouting coupling technique,was put forwarded on the basis of summarizing the relative merits of fire prevention and extinguishing technology on fully mechanized working face in domestic.Practice showed that the technology reduced the harmful gases concentration and gob temperature of working face to the critical value,and ensured the safety production of working face.