Abstract: According to the complicated geological conditions of Zhangxiaolou well in Pangzhuang Coal Mine, the paper creatively puts forward the concept of the rock burst of key trigger layer. By the BP neural network and FLAC^3D technology, the dynamic prediction of 75215 airway floor is realized. The prediction results are consistent with the results of field observation, which verifies the validity of the method. This method can provide reference for safe and fast excavation in 75215 machine roadway and other roadways.