Abstract: In order to effectively reduce the uneven settlement and destructive effect of water-rich sand-soil stratum structure on coal mine inclined shaft, taking the water gushing treatment of an auxiliary inclined shaft in the west of Yushen Mining Area as an example, on the basis of full analysis of wellbore water gushing characteristics and treatment conditions, making use of the grouting difference between sand stratum and cracks in the periphery of wellbore, through on-site grouting test and construction verification, ground vertical drilling is creatively adopted; at the plane position of the drilling point 0.6-0.8 m away from the single-layer structure wall and the grouting level 0.2-0.5 m into the schist and gravel cushion of the wellbore floor, the grouting diameter of ϕ108 mm, the grouting pressure of no more than 1 MPa, the high concentration of single cement slurry (0.7:1-1:1), and the cement-to-water glass double liquid slurry (the volume of water glass accounted for 1% -5%) are used to carry out the directly grouting treatment for schist cushion of the wellbore floor, which effectively seals the cracks around the wellbore floor and the shaft wall. According to the groundwater level recovery test, there is no open water gushing out of the original shaft fracture outlet area, and the water inflow of the shaft in the treatment section is significantly reduced, which indicates that the grouting water plugging technology has certain applicability in the treatment of shaft water gushing caused by the uneven settlement of loose sand strata in the northwest region of China.