Abstract: Aiming at the problem that data encryption and tamper-proof data of the coal mine safety monitoring system are gradually being cracked, and the encrypted monitoring system data has a greater risk of being tampered, by analyzing the current main anti-tampering technologies, main data tampering methods and main data characteristics of the system, considering overall data access user encryption management, data encrypted storage, and data recovery after tampering, combined with the actual and application scenarios of system data, the overall architecture of data encrypted storage and data encrypted storage based on relational database and file storage are designed. The scheme introduces data encryption and anti-tampering methods such as searchable data obfuscation, data encryption, data inspection, and user management shell in relational database storage, and encrypts and stores key data in the form of file encryption backup. The coal mine safety monitoring system with this scheme can effectively prevent data tampering methods such as the replacement method and the deletion method, which are common at present, and has great reference significance in the data encryption and tamper-proof design of coal mine safety monitoring, personnel positioning and other systems.